Warning on neural technique

Jan 24, 2012 Posted Under: Health Care Solutions

A chemical marker that is commonly used to identify newly generated cells in the brain may be distorting the results of studies of neurogenesis, according to research published today in The Journal of Neuroscience1.

Bromodeoxyuridine (BrdU) is a synthetic analogue of thymidine, one of the building blocks of DNA. When injected into animals, it becomes incorporated into newly synthesized DNA, enabling researchers to identify cells that are dividing.

The technique has been used routinely for decades to identify replicating cells, and particularly to investigate neurogenesis, the generation of neurons in the developing brain.

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Gov. O’Malley’s Proposed Maryland Budget Makes the Case for Connecting Kids to Nature

Jan 24, 2012 Posted Under: Health Vocabulary

My Terps are going through a rough patch, but theres one area where Maryland has proven a great leaderits attention to kids outdoor activity and environmental literacy.

Maryland Governor Martin O’Malley announced recently that nearly $23 million will go toward State Park and public land projects in the proposed FY2013 budget, with a special emphasis on their role as resources to connect the state’s families with the outdoors and provide better natural play areas for children:

The State’s parks will also serve as outdoor classrooms for the State’s new environmental literacy requirements.

“State Parks are the epitome of affordable getaways for families, models for living in harmony with nature, and a vital tonic for the mind, body and spirit,” said Tim Casey, Chair of the Governor’s State Park Advisory Commission. “These strate

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HIV/AIDS: “Unprecedented progress”, despite poor funding

Jan 22, 2012 Posted Under: Health Posts

and middle-income countries due to increased access to HIV treatment since 1995 NAIROBI, 21 November 2011 () – New HIV infections and AIDS-related deaths have continued to fall, and the number of people on treatment has risen to nearly 50 percent of those eligible, despite an overall fall in global funding, states a UNAIDS report.

“Even in a very difficult financial crisis, countries are delivering results in the AIDS response,” said Michel Sidibé, executive director of UNAIDS, in a statement. Read full post…

hCG Diet – 2 Years Later!

Jan 15, 2012 Posted Under: Health Posts

Jeff Russell, IAPAMIts been two years since I did 34 days on the IAPAMs hCG diet protocol, so I thought Id give you an update on the effectiveness of the program. As of this morning, Im still within 2lbs of my last injection weight, so am I happy with my results, you bet I am! In reviewing my results, I can safely say that the protocol did everything thing it was supposed to do: it reset my metabolism, reduced my appetite, got rid of those problem fat areas, and all without any type of regular exercise.

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Not Just For Men: Sleep Apnea and Sex Problems

Jan 14, 2012 Posted Under: Health Care Solutions

A great deal more attention and study have been paid to the effects of sleep apnea on men’s sex lives, but the effects of sleep apnea on women’s’ sexual function has received comparatively little research attention. I’ve written before about how sleeplessness can inhibit a woman’s sex life, but we continue to rely on relatively little scientific knowledge of the impact of disorders such as sleep apnea on sex and intimacy for women. It’s welcome news, then, to see another recent study that examined the effects of obstructive sleep apnea on women’s sexual function.

This study included 80 women between the ages of 28-64.

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Vitamin D Heart Controversy

Jan 13, 2012 Posted Under: Health Vocabulary

A recent publication in the American Journal of Cardiology called into question the safety of high dose Vitamin D supplementation In the paper, researchers from Johns Hopkins University School of Medicine investigated a proposed link between Vitamin D levels and an inflammatory protein CRP which is considered a risk factor for heart disease Their conclusions report that levels of D below 21 ng/ml are associated with higher CRP or C-reactive protein This determination came as no surprise However, participants with Vitamin D concentrations significantly above 21 ng/ml also demonstrated elevated or undesirable CRP readings The lead author of the piece, Dr Muhammad Amer, stated that Clearly vitamin D is important for your heart health, especially if you have low blood levels of vitamin D It reduces cardiovascular inflammation and atherosclerosis, and may reduce mortality, but it appears that at some point it can be too much of a good thing

Regular readers of this site know that I frequently recommend Vitamin D testing and supplementation in order to reach 25OHD levels well in excess of 21 ng/ml So, you may be wondering if this current controversy alters my point of view of Vitamin D therapy The short answer is no Im not being stubborn, just basing my opinion on the best possible evidence

In the past several months, at least four intervention studies have been carried out evaluating the impact of Vitamin D supplementation on systemic inflammation Before I describe the results of these trials, please note that intervention trials possess greater scientific validity than population studies In an intervention setting, direct measures of cause and effect are the primary end points Population studies tend to rely on observation and uncontrolled data It is for this reason that intervention trials are often called for to dispute or verify data initially presented in population studies The Johns Hopkins piece is based on population data

The latest evidence pertaining to Vitamin D supplementation and CRP levels indicates that Vitamin D lowers CRP in certain disease states such as in patients with colorectal cancer and kidney disease On the other hand, D supplementation may not have much of an impact on relatively healthy adults of varying ages and weight Please keep in mind that in none of these scenarios did Vitamin D therapy lead to higher CRP levels or other markers of systemic inflammation All four of the previously mentioned trials have an interventional study design

In closing, I want to share some underreported, but highly encouraging news about Vitamin D and cardiovascular health Two current observational studies note that low levels of Vitamin D are correlated with a higher risk of all-cause mortality and heart attack incidence In the mortality paper, the authors recommend Vitamin D levels of between 30 to 35 ng/ml significantly higher than the Johns Hopkins publication In addition, three intervention trials from late 2011 determined that Vitamin D supplementation is capable of improving blood pressure control, insulin sensitivity and lipid levels in at-risk populations including diabetics, hypertensives and seniors All of this research and more points to a valuable role for Vitamin D in the promotion of heart health

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